HYPOTHESIS: THE OPPOSING PULLING FORCES EXERTED BY SPINDLE MICROTUBULES CAN CAUSE SLIDING OF CHROMATIN LAYERS AND FACILITATE SISTER CHROMATID RESOLUTION

Hypothesis: The opposing pulling forces exerted by spindle microtubules can cause sliding of chromatin layers and facilitate sister chromatid resolution

Previous studies indicated that mitotic chromosome structure consists of many stacked layers formed by a mononucleosome sheet folded as a helicoid.This multilayer chromatin structure justifies the cylindrical shape of chromosomes and the transverse orientation of cytogenetic bands, and can explain chromosome duplication by the formation of a transi

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Performance analysis and fleet requirements of automated demand-responsive transport systems as an urban public transport service

The introduction of public transport services by fully automated vehicles can potentially change the way public transit services will be operated, as they allow shifting from rigid scheduled and route-bound services towards flexible, demand-responsive services.This study examines the potential performance of an Automated Demand Responsive Transport

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